Background: Development of health system in Indonesia based on the national health system (sKN). Ihe national health subsystem is a subsystem of financing. To protect the people from financial risks are needed healths financing prepaid systems. There are same patients assumed that the quality of servtce of direct payment system and payment by health insurance are distinguished. The purpose to determine the differences between the quality of service pdyment system INA-CBCs With Fee For Service inpdtients class Il at PKU Muhammadiyah Hospital Bantul. Method: This study used descriptive method. The population research was inpatients class ll at PKU Muhammadiyah Hospital Bantul. The sample size on the payment systems INA-CBC 5o respondents and Fee For Service 5o respondents. The method of data collection using questionnaires. Data analysis performed by different test averrage to the independent samples using Mann-Whitney method. Result and Discussion: Pottents assume the quolity of service at PKU Muhammadiyah Hospital in Bantul distingutshed between fee for service financing and INA-CBGs. They think fee for service finoncing get better service than financing by health insurance.Statistics showed the mean rank of INA-CBGs is 44.4t and the mean rank of Fee For Service is 56.59. Different test dverdge result to the independent samples using Mann-Whitney method indicate there is significant differences between the pdyment system INA-CBCs with Fee Far Service to quality of service. This diff erences is due to the large number of INA-CBGs patients. This is because the communication aspect, long queues and administrotion become complicated so that patients are not satisfied. Conclusions: There are significant differences between the quality of service pdyment system INA-CB6s With Fee For Service.