Background: Workers are populations that are at risk of experiencing health problems, one of which is MSds. Musculoskeletal disorder (MSDs) is a disorder of the musculoskeletal system caused by a non-ergonomic position. UMY cleaning staff are at risk of experiencing MSDs because they do work in the wrong position, repetitive movements, monotonous, which can lead to disability, as well as decreasing work productivity. This study aims to determine the description of musculoskeletal disorders due to work that occurs in janitors at Muhammadiyah University of Yogyakarta based on sex, age and years of service. Research Metods: The method of this research is quantitative descriptive on the cleaning staff of UMY amounting to 94 according to the inclusion criteria, namely the sample taken by the Simple random sampling instrument used is the Nordic Body Map. Research Result: MSDs category in UMY cleaning officers is in the category of complaints that arise medium and frequent complaints. The category of work-related musculoskeletal complaints on janitors based on sex was mostly male (85.62%). The respondents category of musculoskeletal complaints due to work on janitors based on age is at least 61-70 years old (8.5%). The work category of musculoskeletal complaints on janitors based on the work period most often occurs in the 1-10 year work period (83.0%). Conclusion: The majority of respondents have complaints in the moderate and frequent categories. The majority of complaints were experienced by male workers, aged 61-70 years and working period 1-10 years. Workplace institutions are expected to pay more attention to these WMDs so that they can make prevention efforts so as not to have a greater impact, for example a decrease in work productivity.