Background: Sleep is a common behavior that plays an active role in processes such as synaptic plasticity and memory function, emotion regulation, metabolic function and energy balance, macromolecular biosynthesis, processing toxins and metabolic waste. Changes in the duration and quality of sleep in pregnant women, related to hormonal, psychological and metabolic changes. As many as 11% of pregnant women are less than 7 hours per night in the first trimester, 20.6% in the second trimester and 40.5% in the second trimester of pregnancy .Pregnant women who sleep <6 hours at the beginning of pregnancy are at risk of having high blood pressure in the third trimester of pregnancy. Women who has experience a decrease in quality of sleep during pregnancy are at risk of 20% experiencing lengthening the time of birth. Research Objectives: This study aims to determine the correlation between anxiety and sleep quality of pregnant women. Methodology: This study uses a quantitative method with correlative analytic method using cross sectional approach.. Participants in this study amounted to 96 pregnant women, participants in this study were determined using purposive sampling. The instrument used to measure sleep quality and anxiety in this study was PSQI and Z-RAS.. Result: The results showed that there was a significant relationship between anxiety and sleep quality in pregnant women, with P value 0,004. Anxiety is one of the stress response that can be a threat to both physiologically and psychologically or may occur in people who are not be able to identify the source of stress they experienced. Anxiety and depression in response to stress can stimulate our body to activate the fight or flight response, it can make the people withstress will have difficulty to relax because muscles tighten and the heart beats faster as the effects of the fight or flight response. Difficulty to relax can cause pregnant women experience sleep problems. Anxiety can lead to increased sympathetic nerve activity and parasympathetic nerve activity decrease. Conclusion: There is a significant correlation between anxiety with sleep quality in pregnant women.