Medissina I Clinic, Which is located on Taman Mutiara Residence, Building no M-7, Rt 01 Rw 05, Karang Mekar Cimahi, Postcode 40523, still had unsynchronized processing and inputting data between pharmacy and clinic. Drug purchase record and Doctor’s fee calculation had also still done manually. f. So that without realized, there’s a calculating mistake or incompatible data and also it’s hard to monitoring employee , became a serious problem in this clinic This Application designed using C# programming language based desktop application, and with Software development life cycle (SDLC) method. This Desktop application can help the owner to organize and processing sales data effectively and efficiently. Beside that, the owner also can do supervision on any input and output activity whenever and wherever they were, so its become more flexibility onto arrangement and created a neater operating management. Testing phase on system work with standard functioning to record any transaction happened accordingly. Owner also can get Doctor’s fee data easily and more accurate. On the Employee side, they are facilitated by only needed to open 1 application which can cover both drug and clinic operation.