This research focuses on the emergence of Russia-Syria-Iraq-Iran Alliance caused by common threat from United State of America (USA) hegemonies and anarchical international structure that stimulate insecurity. Under qualitative approach, this research mostly uses content analysis method. The result of this research shows that Russia has long history of diplomatic and economic relation towards Syria, Iraq, and Iran. The initiation of Russia-Syria-Iraq-Iran alliance formulated since the Syrian Civil War emerges. The alliance point’s of agreement is to gather, process, and analyze the information related to Middle East area and terrorist group Islamic State of Iraq and Syria.