Snail mucus that contains Allantoin which functions as a skin moisturizer, and Honey is emollient and contains Flavonoids and Amino Acids which are believed to moisturize the skin. These two natural ingredients are combined in a peel-off gel mask formula. This study aims to determine in physical properties of snail slime peel-off gel masks with variations in the addition of honey, determine the degree of irritation and determine the activity of increasing skin moisture. The design of this study uses an experimental method with formulas that have been optimized from the results of previous studies. Peel-off gel masks made into 5 formulas namely FI Base, FII Base, FI, FII, and FIII using Polyvinyl Alcohol (PVA) and Carboxy Sodium Methyl Cellulose (CMC-Na) as a gelling agent.. This formula will be tested with a variation of the addition of 6% honey, the parameters tested in the form of physical properties including organoleptic test, pH, spreadability, adhesion, viscosity, and drying speed. Skin moisturizing activity was tested using a RoHs 56-5D model skin detector. Changes in the humidity level of respondents before and after using a moisturizing gel was tested using a RoHs 56-5D model skin detector of 5 respondents. Statistical test of the difference between humidity analyzed using the One Way ANOVA test. The irritation test was carried out using two albino rabbits by making 6 patterns on the rabbit's back using the Draize method and observed erythema and edema at the hour to 24 hours, 48 hours, and 72 hours. The results of this study found that, the peel-off gel masks form in organoleptic there was no significant difference, the pH values of all formulas were the same ie 5.5 ± 0. the drying speed of the formula were successively from Base FI, Base FII, FI, FII, and FIII, namely 26.44 ± 0.64 seconds; 25.92 ± 0.40 seconds; 27.13 ± 0.15 seconds; 29.65 ± 0.59 seconds; and 29.6 ± 0.52 seconds, spreadability strength respectively were 3.99 ± 1.09 cm, respectively; 4.66 ± 1.37 cm; 3.63 ± 0.92 cm; 4.67 ± 1.44 cm; and 3.76 ± 1.18 cm, successive adhesion are 78.18 ± 6.62 seconds; 63.43 ± 5.94 seconds; 58.29 ± 12.74 seconds; 43.83 ± 13.74 seconds; and 38.44 ± 14.10 seconds, viscosity respectively 2048.33 ± 7.09 cPs; 2069.33 ± 3.51 cPs; 2315.00 ± 3.61 cPs; 2301.33 ± 8.33 cPs; and 2314.67 ± 6.11 cPs . These results fall into the category of semistiff type peel-off gel requirements. Based on the test of the effectiveness of skin moisturizers using the One-Way ANOVA statistical test both formulas did not differ significantly in increasing skin moisture with a significance value of 0.323 . While the irritation test results showed variations in the formula FI, FII, and FIII masks included in the category of slight irritation while the base formula FI and base FII did not cause irritation.