A two-phase flow is part of a multiphase flow which only involves two forms of a substance in a stream. In general, two-phase flow is often found in oil and gas piping systems, nuclear reactors, geothermal, cooling electronic devices. The purpose of this study was to obtain primary data on an experimental study of the characteristics of a two-phase flow of air-water + 7% butanol in a small pipe with a slanted position of 40˚. Primary data taken are: Video flow patterns and pressure gradients. This research was conducted using a test section in the form of a small pipe with a diameter of 1.6 mm in length with 130 mm in length and a slope of 40 ° to the horizontal position. The working fluid is air-water distilled water with 7% butanol mixture. By varying the superficial velocity values of gas and water in the range JG = 0.025 - 66.3 m / s and JL = 0.033 - 4.935 m / s. In this study using a visualization method with the MOV to AVI program and then processed with virtual dub for flow patterns, digital image processing with the MATLAB R2014a program for vacuum fractions and for pressure gradients using the pressure transducer fluid pressure sensor connected to the computer. In this study the flow patterns obtained are: bubble, plug, annular, annular and churn slug. Flow patterns that are formed are then justified and mapped based on variations in superficial velocity, flow pattern maps are also compared with the results of previous studies. The value of the vacuum fraction is influenced by the varied JG and JL and the flow patterns that occur. The pressure gradient value is influenced by the superficial velocity of liquid or gas. The pressure gradient will increase due to the effect of JL with a range of 0.091, 0.232, 0.539 m / s and variations from JG 0.025 - 66.3 m / s. The pressure gradient also increased due to the effect of JG in the range of 0.207, 3, 9.62 m / s and variations of JL 0.033 - 4.935 m / s.