The most common problem in terms of dental and oral health is the high number of elementary school children who suffer from dental caries, WHO reports 60-90% of primary school-age children in the world have experienced dental caries. Dental caries that occurs in children must be addressed immediately because it can make a very detrimental impact. Various efforts were made to deal with dental caries problems that occur in children, namely by preventive measures. The examples of prevention efforts are fissure sealant and preventive resin restoration (PRR) treatments. The purpose of this study was to determine the success rate of fissure sealant and PRR treatment at RSGM UMY in pediatric patients. The type of research used in this study was observational research with a cross-sectional design. This research was carried out by taking all medical records of pediatric patients in RSGM UMY in the period of 2017 which were treated with fissure sealant and PRR, in this study 114 treatments in fissure sealants and 86 treatments in PRR was determined. The results showed a percentage of the success of fissure sealant treatment that is equal to 98 people (86%) and unsuccessful by 16 people (14%), while the percentage of success of PRR treatment was 79 people (91.9%) and unsuccessful for 7 people (8.1 %). The results of the success rate of fissure sealant and PRR treatments were analyzed using descriptive statistical test using the SPSS software program. The conclusion of this study is that the treatment of fissure sealant and PRR both showed high success rates but the success rate of PRR treatment was higher than the success rate in fissure sealants.