The study aims to determine the confidence of orphans in Purbalingga, the differences in the confidence of orphans living in orphanages with families, and the causes of these differences. The type of research was mixed methods (quantitative supplemented with qualitative) with 40 orphan respondents (20 orphans in the orphanage and 20 in the family) and supported by 4 informants of the orphanage studied. Data collection techniques using questionnaires, interviews, observations, and documentation. Quantitative analysis uses the formula of independent sample t test, while for qualitative analysis uses interactive models. After data analysis, the following conclusions are obtained: (1) the confidence of orphans in orphanages tends to be high, whereas in families it tends to be moderate; (2) the confidence of orphans in orphanages is higher than in the family (tcount 3.608> ttable 1.686); (3) higher self-esteem of orphans in the orphanage compared to the family mainly due to the pattern of care in the orphanage studied (Muhammadiyah Bobotsari Orphanage, Muhammadiyah Bukateja Orphanage, Muhammadiyah Mandhanisiwi Purbalingga Orphanage, Muhammadiyah Nurussalam Kemangkon Orphanage) better than in the family, because the caregivers are educated both academically and practically, and motivated to carry out their duties as worship seeking God's pleasure.