Interprofessional Education (IPE) is the collaboration two or more different students health profession to improving interprofessional collaboration with the result of improving quality of patients life. Learning process IPE at University Muhammadiyah Yogyakarta held in Asri Medical Center (AMC). Learning process will be provided patients to especially for outpatients with some disease. The optimality of health care will be provided with a high quality of patients life. A Quality life is the someone condition who have seen from a psychological condition, welfare emotional, physical and mental health, have a physical ability to do the things to do every day. The research aims to determine the quality of outpatients life IPE Asri Medical Center Yogyakarta. The research is descriptive analysis research with cross sectional approach. The sampling technique using totally sampling technique. There are 10 outpatients IPE be given the questionnaires THE WORLD HEALTH ORGANIZATION QUALITY OF LIFE (WHOQOL) –BREF with 26 questions comprising 4 dimensions quality of life. The first score measurement from research instrument WHOQOL –BREF will be transform to scale 0-100 and categorized to scale categories quality of life based on 0: mortality; 1-55: low; 56-79: medium; 80-99: high and 100: perfect. The result of this research available to quality of patients life toward learning process of IPE in AMC is high with an average 84.97 ± 1.53. The quality of patients life by four dimensions, sorted from biggest there are social relationships, psychological health, environmental and physical health.The conclusion of this result is the quality of outpatients life IPE AMC is high.