interprofessional education (IPE) is one of them education integrated to increased capacity collaboration.There are still many student who does not be ready for ipe because knowledge those less about IPE. Students have having knowledge enough about ipe will have the positive on IPE. FKIK MuhammadiyahUniversityYogyakartahas started exposed to IPE proven from 2013 model IPE has been applied.But a concrete the application of ipe in fkik muhammadiyah university yogyakarta remains to be seen. Objective: to know relations between the level of knowledge with readiness students MuhammadiyahUniversityYogyakarta face interprofesional education (IPE). Methods: the research is research quantitative.This research using design cross sectional.Population in research this is a student fkik 2012 as many as 576 students. The sample of the used is as many as 236 respondents.Analysis the data used was analysis univariat and analysis of bivariat with using formulas chi square. Result: most students FKIK having a level knowledge nice about ipe with 142 respondents (60,2 %).The majority of respondents having readiness face of IPE at the ready with 182 respondents (77,1 %). Closeness between the level of knowledge with readiness students Muhammadiyah YogyakartaUniversity face interprofesional education (IPE) is located in the and he 0,428. Conclusion: there are signifikasn relations between between the level of knowledge with readiness university students muhammadiyah yogyakarta face interprofesional education (IPE).