Therapeutic communication is conscious and activities focused on the patient's recovery. The purpose of this study was to determine the steps therapeutic communication between nurses and patients with psychiatric disorders class C in Ghrasia Psychiatric Hospital Yogyakarta. The method used is descriptive qualitative research method for this study will explain, illustrate, describe, record, analyze and decipher everything related to the problems examined with the object of research. Data was obtained through interviews, observation, and literature. The technique of taking informants using snowball sampling. Data were analyzed using data collection, data reduction, data presentation, and conclusion. Test the validity of test data using triangulation. The data have been successfully obtained by investigators will be collected and recorded in research activities that sought truth. The results showed therapeutic communication measures undertaken by nurses with a class C patients psychiatric disorders in the Mental Hospital Daerah Istimewa Yogyakarta Ghrasia includes four phases, namely; phase prainteraksi, nurses collected data, explore feelings, fantasies and fears themselves, analyzing the strengths of professional self and limitations, and make a plan for a meeting with the patient, the orientation phase, the nurse must first build a trusting relationship between nurses and patients, working phase, nurses implement the strategy active listening, and the last phase of the termination, the nurse did an evaluation of the communication process in the previous phases