This research is entitled The Application of Tempe Industrial Liquid Waste and Urea on the Lettuce (Lactuca Sativ) Growth and Results. The research was done in UMY research field on August 2016 to September 2016. The research objective is to find out the influence of tempe industrial liquid waste toward Lettuce (Lactuca Sativ) Growth and to get the appropriate dose of the boiled soy liquid waste for lettuce (Lactuca Sativ). This research was done using the experimental method arranged in Completely Randomized Design (RAL). The research was done using single factor design of the tempe industrial liquid waste concentration on lettuce. The treatments given are; N1= (100% N-urea+0%N – Tempe liquid waste), N2= (75%N – urea + 25% N - tempe liquid waste), N3= (25% N –urea + 75% N – tempe liquid waste), N4= (0% N –urea + 100% N – tempe liquid waste). There are 4 treatments. Each treatment was repeated three times that there were 12 experimental units. Each treatment consisting of 5 plants poly bags that there were 60 lettuce experimental units from 4 treatments. The parameter observed covers the observation of plants vegetative growth (the plants height and leaves number) and the generative growth (fresh weight crown, dry weight crown, root dry weight, root length, and yield ). The research results showed that The Application of Tempe Industrial Liquid Waste and Urea gives the same influence on the lettuce cultivation that tempe industrial liquid waste can replace urea in lettuce cultivation. Meanwhile, the application of combined tempe industrial liquid waste and urea can provide the need of N in lettuce cultivation.