The research aims to analyze the influence of profitability, growth opportunity, firm size and investment opportunity set (IOS) toward firm value with capital structure as an intervening variable. The independent variable in this study is the profitability, growth opportunity, size and investment opportunity set with capital structure as an intervening variable, and firm value as an dependent variable. The object in this study was property companies, real estate and building contruction listed on Indonesia Stock Market or Bursa Efek Indonesia (BEI) during 2010-2015. In this study, sample of 38 companies were selected using purposive sampling. The data analysis technique in this research was conducted using multiple linear regression with EVIEWS 7 software. The analysis method used classical assumption test, composed from; multicollinearity test, heteroskedasticity test and autocorrelation test. The hypothesis used T-Test, F-Test, and Determinant Coefficient Test. Based on the analysis that have been made the result are the investment opportunity set and capital structure are significantly influence on firm value. Profitability, growth opportunity, and firm size are not significantly influence on firm value. Growth opportunity and firm size are significantly influence on capital structure. Profitability and investment opportunity set are not significantly influence on capital structure. Lastly, capital structure can be an intervening variable from growth opportunity variable and firm size