This study aims to find out about the influence of Perceived Ease and Perceived Benefits to Using E-banking interest Moderated By Computer Self Efficacy. Respondents in this study were students at the University of Muhammadiyah Yogyakarta Management course that has or has not used E-banking services. In this study respondents used were 120 respondents were selected using random sampling method. Anailisis tool used is the Hierarchical Multiple Regression Analysis. Based on the analysis that has been done shows that the perception of the ease and benefits of computer self-efficacy moderated by the positive effect on interest in using E-banking.