This study aims to analyze the relationship of workload, work stress, and motivation with job burnout. The information from this research is very important for business related business as a consideration for implementing the improvement of work quality in order to avoid burnout. The object of this research is done in Warung SS Yogyakarta. The subject of this research is on stall employees of SS Yogyakarta. Sampling technique using purposive sampling. Methods of data collection using questionnaires obtained 97 respondents. The analytical tool used in this study is multiple correlation with the help of SPSS. The results showed that workload was significantly related to burnout. Work stress is significantly associated with burnout. Motivation is negatively related to workout fatigue (burnout). The value of determination in this study amounted to 0.439 or 43.9%. This means that these three variables have a relationship with job fatigue of 43.9% and the remaining 56.1% have relationships with other variables outside this research variable.