Students are one of subjects who have high risk in needle stick and sharp injury at hospital. It can be caused by lack of clinical education assistaning. Directional Bed Side Teaching (BST) was one of effort to solve this problem. Purpose of this study was to analyse the effectiveness of BST toward needle stick and sharp injury prevalences in clinical practice students of PSIK FKIK UMY. This study was quasy experimental without control group. Sampel of this study were preceptors and 31 students with simple random sampling. Binary logistic was used as analysis data in this study. Based on binary logistic analisis with expectation B score (Exp B). It showed that implementing of BST variable Exp (B)= 3,429 toward needle stick and sharp injury in con dent 95%.. The implementing of BST had positive correlation with neddle stick and injury sharp object. Preceptor suggested for assisting the students regarding to needle stick and sharp injury.