This study aims to analyze the Influence of Risk Profile, Good Corporate Governance, Earning, and Capital on Sharia Banking Profitability in Indonesia. The object of this research is all general Islamic banking in Indonesia. In this study there are 11 banks selected by using purposive sampling method. The analysis tool used is Multiple Linear Regression. Based on the analysis, the results showed that Credit Risk as measured by Non Performing Finance has a negative and significant impact on bank profitability. The risk of liquidity measured using Financing to Deposit Ratio does not affect on profitability, Good Corporate Governance also does not affect on profitability and Earning measured by Expense Operational compared to Operational Revenues have a significant negative effect on profitability and Capital Adequacy Ratio as measured by Capital Adequacy Ratio has a significant negative effect on the profitability of sharia banking.