The objective of the emprical study is to examine and to analyze the influence of corporate social responsibility disclosure, profitability, leverage, and growth companies to earnings informativeness proxied by earnings response coefficient on manufacturing companies listed on Indonesian Stock Exchange and consistenly follow the PROPER assessment at year 2014-2015. This research uses moderting variabel environmental performance. Data for this research were obtained by Indonesian Capital Market Directory (ICMD), the Indonesia Stock Exchange homepage, the company's annual reports, environment minister’s decision and online data. Sample that used in this research are 60 go public manufacturing companies listed in Indonesian Stock Exchange and consistently follow the PROPER at year 2014-2015. The sampling technique used was purposive sampling method. This research uses Modertor Regression Analysis (MRA). The research results showed that corporate social responsibility disclosure and leverage has a negative influence to earnings informativeness, while profitability, and growth companies a positive influence to earnings informativeness. The test results in moderating variable that environmental performance strengthen the relation corporate social responsibility disclosure and earnings informativeness, environmental performance weaken the relation leverage and earnings informativeness, environmental performance strengthen the relation profitability and earnings informativeness. and environmental performance strengthen the relation growth companies and earnings informativeness