Background: In Indonesia the level of undesirable events in 2007 was 46.2% and in 2010 increased to 63%, so patient safety was an important factor to pay attention. Firdaus Clinic is primary health care that are preparing the process of clinic accreditation, improvement of various systems, including patient safety. The purpose was to determine the percentage change in the dimensions of patient safety achieved after, compared to before the application of accreditation documents. Methods:Using a questionnaire that consist of 12 dimensions from AHRQ(Agency for Healthcare Research and Quality) at 2004 which has been translated, using secondary data that taken before the application of accreditation documents on October 2017, and primary data on July 2018 after the application of accreditation documents. Results and discussion:An enhancement in the 10 dimensions of patient safety culture after the application of clinic accreditation documents. The highest change(44%) in the dimension of feedback and communication, there was no change in the dimension of perception about patient safety, and a decrease in the dimension of frequency of reported events (6%). Overall 12 dimensions, the average change increased by 20.2% after the application of accreditation documents. Conclusion:The application of clinical accreditation documents can improve patient safety culture. Keywords: Clinical accreditation, patient safety culture