The purpose of this research is : to find out the effectiveness of Interactive monopoly game towards depression score on the elementary students in SD muhammadiyah Tamantirto Kasihan Bantul, to analyze the subjects’ depression score in the experiment group before and after intervention. The instrument used to collect the data in this research was questionnaire. The type of this research was Quasi Experiment which included Pretest – Postest design. The population was male and female elementary students in SD muhammadiyah tamantirto kasihan bantul. The data analysis was descriptive using SPSS program. The result of this research shows that : there is no effectiveness of Interative Monopoly game towards the depression score on the elementary students in SD Muhammadiyah Tamantirto Kasihan Bantul, the analysis of the subjects’ depression score before and after intervention was using T-test sample paired test, resulting in sig.603, meaning that it is more than 0,05. Therefore, it can be concluded that there is no significant difference between the pre-test and the post-test of the experiment class croup. The T-test independent test result is: intervention class-control Sig (1,000).