Background: Age estimation of individuals through dental panoramic radiographs should be an important process of identifying forensic odontology. Dental age can be use to estimating the chronological age of individuals.There are two latest methods modified by Willems and Blenkin-Taylor Objective: To find the differences between Willems method and Blenkin-Taylor method in estimation age using panoramic radiographs Method: This study used observasional analytical with cross sectional study design. The sample for the study consisted of 95 radiographs (48 male and 47 female) is evaluated by Willems and Blenkin-Taylor methods to obtain dental age. The differences between chronological age and dental age were statistical analysis carried out by independent t-test of SPSS 15.0 test for Windows. Results: the Willems method p = 0.266 in male and female p = 0.415, Blenkin- Taylor method p = 0.191 in male and female p = 0.300, (p value> 0.05), it means no significant difference between chronological age and dental age according to the Willems method and the Blenkin-Taylor method in female and male groups. Conclusion: There is no difference between Willems method and the Blenkin- Taylor method, in the age estimation using panoramic radiographs in patients at the Dental and Oral Hospital of Muhammadiyah Yogyakarta University