| dc.contributor.author | Sugihartini, Nining | |
| dc.contributor.author | Kurniawan, Muhammad Fariez | |
| dc.contributor.author | Yuwono, Tedjo | |
| dc.date.accessioned | 2020-05-31T02:00:55Z | |
| dc.date.available | 2020-05-31T02:00:55Z | |
| dc.date.issued | 2020-05-08 | |
| dc.identifier.issn | 1995-7157 | |
| dc.identifier.uri | http://repository.umy.ac.id/handle/123456789/34541 | |
| dc.description.abstract | The essential oil of clove has acted as an anti-inflammatory. This study aims to detect the influence of the various
component of oleic acid and propylene glycol as an enhancer to the anti-inflammatory activity of essential oil of
clove in emulgel. The composition of oleic acid -(AO) and propylene glycol -(PG) in emulgel was based on
Simplex Lattice Design method are FI (100% 0% AO-PG), FII (50% AO-50% PG), FIII (0% AO- 100% PG).
Emulgel was evaluated for anti-inflammatory activity by using male mice strain BALb/C which was induced
inflammatory with croton oil. The results of the study showed the increasing concentration of propylene glycol
caused the decreasing of the value of COX-2 (p>0.05) and the thickness of epidermis (p <0.05). On the other
hand, the increasing concentration of propylene glycol caused an increase in the number of inflammatory cells
(P>0.05). The optimum composition of enhancer in emulgel of essential oil of clove was 100% of propylene
glycol. | en_US |
| dc.description.sponsorship | Grant Research Tim Pascasarjana 2016 | en_US |
| dc.language.iso | en | en_US |
| dc.publisher | Deanship of Academic Research, University of Jordan | en_US |
| dc.subject | Anti-inflammatory, Emulgel, Enhancer, Oleic acid, Propylene glycol. | en_US |
| dc.title | Anti-inflammatory Activity of Syzygium Aromaticum Essential Oil in Emulgel | en_US |
| dc.type | Article | en_US |
