Background : Health workers have a responsibility in preventing medication errors that occur from the prescription process to the administration of drugs. Medication errors are serious problems that have an impact on increasing the duration of hospitalization and treatment costs, patient mistrust which is usually followed by patient dissatisfaction with health care. The purpose of this study was to determine the risk factor analysis of medication errors in outpatient and inpatient care at the At-Turots Islamic Hospital. Methods : This study used a mix of research methods, namely quantitative and qualitative research methods. The population was doctors, midwives, pharmacists and assistant pharmacists and nurses at At-Turots Hospital, totaling 42 people. The sample collection technique used total sampling technique. Quantitative data analysis used techniques of descriptive and qualitative data analysis with Miles and Huberman models including data collection, data reduction, data display and conclusion drawing / verification. Results : The risk factor for medication error related to low category of profession (71.4%) was seen from the health official liking and being interested in his profession supported by knowledge and understanding related to the available medicines both dosage, method of use, administration of drugs according to the route and side effects. The risk factors for medication errors related to low category of facilities and infrastructure (52.4%) are indicated from a comfortable work environment because it is far from noise and has adequate lighting, medicines are also neatly arranged and there are SOPs related to the profession. The risk factors for medication errors related to moderate category of management (81.0%), which shows that management facilitates the reporting of medication error events. Conclusion: Risk factors for medication errors in hospitals may still exist, but efforts are being made to improve patient safety. Risk factors for medication errors related to the health profession, facilities and infrastructure and management need to be a priority so that the quality of patient safety can improve.