This study is conducted to analyze the profitability which is proxied by ROA, leverage which is proxied by DER, company size which is proxied by SIZE, and the asset growth which is proxied by GROWTH in manufacturing business registered in Indonesia Stock Exchange /Bursa Efek Indonesia (BEI) in the year of 2011- 2014. The research population is public companies registered in Indonesia Stock Exchange in which manufacturing business as the samples. This study used purposive sampling method using 97 samples from 29 manufacturing business which shared dividends during the research process. The data analysis used in this study was classical assumption test and hypothesis test using multiple linear regression. The result of the study shows that the profitability, the company size, and the asset growth have significant effect on the dividend policy with probability value less than 5%.