This study aims to determine the effect of firm size, profitability, liquidity and asset structure of the capital structure. The data in the analysis is the annual report and financial statements of companies listed on the Indonesia Stock Exchange in 2010-214. The number of samples in this study consisted of 114 companies during the 2010-2014 period, The company selected using purposive sampling method. The analytical tool used was SPSS version 15.0. The statistical method used to test the hypothesis is multiple regression analysis. Variables measured by size of companies size, profitability variables is measured by a ratio on equity, liquidity and variables measures by current ratio and the structure of assets is measured by TA and capital structure are measured using debt equity ratio. The result showed that the variable of company size, profitability, liquidity and asset structure and significant effect on the capital structure. As well, the dividend a significant negative effect on stock price.