Background : Diabetes is a chronic disease which happened when pancreas produces insulin less than needed or when its used by the body ineffectively. Epidemiologycally, in 2030 the prevalence of Diabetes Mellitus (DM) in indonesia will reach 21,3 million of people. Neuropathic is a long term complication which commonly for diabetes, it is influence around 50% of diabetic. The main factor of the reason neuropathic is from the duration and either the degree of hyperglicemia, dyslipidemia, body mass index (BMI), smoke, hypertension and height as risk factor of DPN, However, there is still a limitation of the evidence. The aim of this study is to find out the relationship of Risk factor of Dibaetes Mellitus toward the degree of neuropathic diabetic from the group of PERSADIA RSI Amal Sehat Sragen. Methods : Cross sectional study conducted to 66 members of PERSADIA. Data Medical recorded were used such as; gender, wight and height to get the body mass index (BMI), blood pressure to find out the data of its hypertension and smoke history. Data analyzed by using kruskal wallis test and chi-square to find out the relationship between Risk factor of Dibaetes Mellitus toward the degree of neuropathic diabetic that is BMI, hypertension and smoke history. Result : There were 66 respondents used in this study: the result showed that 12 respondents (18,2%) have no neuropathic, 31 respondents (47%) light neuropathic and 23 respondents (34,8%) medium neuropathic. The result from gender showed that is woman 38 respondents (57,6%), the highest respondent from normal BMI was 22 respondents (33,3%), the highest respondent from normal hypertension was 38 respondents (57,6%) and the highest respondent from no smoke history was 47 respondents (71,2%). The study showed that there was a relationship between Risk factor of Diabetes Mellitus toward the degree of neuropathic diabetic that was BMI (p=0,000), hypertension (p=0,000) and smoke history (p=0,026). Conclusion : There was a relationship of Risk Factor (BMI, hypertension, smoke history) of Diabetes Mellitus toward the degree of neuropathic diabetic from the group of PERSADIA RSI Amal Sehat Sragen