Grouper fish (Ephinephelus fuscoguttatus) is one of the most potential fishery commodity product in Indonesia, It also has a high value and has been exported to many countries, such as Hong Kong, Taiwan, Singapore and Japan. Indonesia is the third largest grouper fish producer in the world after Hong Kong and Taiwan. Each year national grouper fish production demand experiences increases as much as 9, 61% since 2010-2014 (KKP, 2014). A study towards national grouper fish became crucial to be done knowing that Indonesia’s position as one of the largest grouper fish producer and exporter in the world. The purpose of this study: 1) To analyze agribusiness system of grouper fish in Indonesia, 2) To analyze national grouper fish agribusiness competitiveness. The data used in this study is secondary data, analyze using descriptive qualitative method. Materials used in this study is system framework and Porter Diamond Theory. The Data analyze shows that grouper fish’s agribusiness system is not integrated yet. Needs to be more observed including live grouper fish marketing governance that is not yet efficient. From the four main components in Porter’s Theory, natural resources factor is the most competitive factor in Indonesia recently, furthermore to achieve excellent competitiveness require increasing on competitiveness in other main components. Indonesia’s commodity grouper fish can reach its maximum potential by increasing competitiveness in all main agribusiness system.