THE EFFECT OF AIR FRESHENER EXPOSURE ON CORNEAL THICKNESS OF WHITE RAT (Rattus norvegicus)
NUGROHO, PAJAR SIGIT
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The use of air freshener at this time more often found in various places, whether in of ces, homes, and public areas. Air freshener contain various volatile organic compounds that are harmful to health, such as formaldehyde. Air freshener spray and gel air freshener is the form most commonly used. Chemical composition between the form of air freshener with each other is different. One organ that is susceptible to exposure of air freshener is the cornea of the eye. This study aims to assess the effects of air fresheners on the cornea of the eye and compare the effects of two forms of the air freshener.The subjects of this study were 18 rats, divided into three experimental groups, the control group (without treatment), the treatment group freshener spray and gel air freshener treatment group. In the treatment group performed freshener exposure for 8 hours / day for 15 days. Data is taken by measuring the thickness of the cornea under a microscope. The experimental results were analyzed using Kruskal Wallis test. Results of post hoc test showed a signi cant difference between the groups with the control gel air freshener p=0.037 (p<0.05), and between the spray air freshener to control p=0.025 (p<0.05). No signi cant difference demonstrated by a group of air freshener spray and gel with p=0.631 (p> 0.05). This suggests that the exposure of air freshener give negative effect to the histological changes in the cornea, but the effect of exposure spray and gel air freshener, there is no signi cant difference.