Kawasan Tanpa Rokok (KTR) is a government program implementation to address the high number of smokers in Indonesia. KTR is a mandate of Regional Regulation number 5 of 2014 explaining that the establishment of non-smoking areas in public facilities, is health care, children playground, teaching and learning places, places of worship and workplace. The researcher chooses SMA N 1 Temon as research place. SMA N 1 Temon is part of the campaign program KTR by Dinkes Kulon Progo. The purpose of this program so that SMA N 1 Temon can respond to the dangers of smoking through a media campaign. This research examines the opinion SMA N 1 Temon to campaign conducted Dinkes Kulon Progo. This research is descriptive qualitative research. The data collection techniques in this study in the form of interviews, observation and documentation. After the data obtained is complete then the next researcher performs data analysis in the form of data collection, data reduction, data presentation and subsequent discussion to draw conclusions. Through this research, researchers found out how the formation of opinions through a campaign. The effect of the campaign tool used becomes a separate point for students in understanding the KTR campaign message. However, with the limitations of campaign tools and also the selection of messages that are less effective, so the stigma of danger of smoking is still underestimated by informants in this study.