Background: Menstruation problem is commonly found in all women especially moslem women that is closely related to religious service matter. It is important for a woman to know the difference between menstruation blood and other bloods like istihadhah blood. According to Islam religion, there are some ways to differentiate both bloods. One of them is by seeing the menstrual habit of the women in their environment. Some women who live together and often do activities together will probably have similar menstruation cycle and this is what is called as menstruation synchronization. Menstruation synchronization can be influenced by some factors like menstrual hygiene and stress level factors. Research Objective: Finding out the description of menstruation synchronization on first year female residents in University Residence (UNIRES) of Universitas Muhammadiyah Yogyakarta with the factors that can influence the menstruation synchronization. Research Methodology: The research was non experimental one with pure descriptive design. The subject of the research was 64 respondents taken with simple random sampling technique. They were the first year female residents in UNIRES UMY. Menstruation synchronization was measured with menstruation synchronization formula (Weller & Weller, 1997), while the menstrual hygiene and the stress level with questionnaire. The data analysis used univariate analysis. Research Result: Based on the result of the univariate analysis, the majority of the respondents who have menstruation synchronization are 41 respondents, while the majority of the respondents who have good menstrual hygiene are 51 respondents and the majority of the respondents who have normal stress level are 29 respondents. Conclusion: Most of the first year female residents in UNIRES UMY had regular menstrual cycles of 79.9%, having menstrual synchronization as many as 64,1%, had good menstrual hygiene behavior during menstruation as many as 79,9% and have a normal stress level of 45.3%