Background: Single root canal treatment requires continuous and longer period of time, thus the treatment satisfaction of patients can be affected. It can be influenced by several factors, such as: tangibility, responsiveness, assurance, reliability, and empathy. Objective: To determine the factors that affect treatment satisfaction of patients towards single root canal treatment quality in RSGMP UMY in the year of 2016- 2018. Method: The type of research used is observational research with cross sectional approach that is descriptive non-analytic. Simple random sampling was used for sampling which was taken randomly for 52 respondents who are undergoing single root canal treatment in RSGMP UMY by fill out an online questionnaire directly. Result: Based on the result, it is obtained that 57.14% are satisfied, 36.08% are very satisfied, 6% less satisfied, 0.55% dissatisfied, 0.37% very dissatisfied with the ability of the clinical students performance. The factor that should be improved is reliability. Conclusion: Overall the patients were satisfied with single root canal treatment that performed by the clinical students