Student-Centered Learning (SCL) is one of the approaches used by pre-service teachers during teaching practicum. This study aims to investigate pre-service teachers’ perceptions on implementing SCL in their teaching practicum. Second, it aims to investigate pre-service teachers’ perceptions on the difficulties they had when implementing SCL. Last, it aims to investigate pre-service teachers’ perceptions on the solution to solve the difficulties in implementing SCL. This study used qualitative descriptive design. The interview was used as the data collection method. In this study, the researcher used interview guideline as the research instrument. The participants were four pre-service teachers of a private university in Yogyakarta. The findings showed conceptual understanding of SCL perceived by pre-service teachers’ perceptions was that the method that make students participate actively in teaching learning process. That method also focuses on the students, where the role of the teacher is only as a facilitator and controller in the activity of students. The activities in implementing SCL based on pre-service teachers’ perceptions included making group or peer discussion to answer the question and making creative poster. Games also became one of the activities in implementing SCL. Pre-service teachers felt happy when they succeeded in implementing SCL, although they felt tired and nervous in the beginning of implemented SCL in their teaching practicum. The difficulties faced by pre-service teachers in implementing SCL, were making students participate actively, controlling the students, preparing the materials, and making students understand about the instructions. The solutions to solve the difficulties in implementing SCL based on pre-service teachers’ perceptions were conducting the activities that make students more active, finding more resources of the material, controlling the students and repeating the instruction until students understand.