This study aims to analyze the effect of asset structure, company size, growth rate, profitability, and business risk on capital structure. The object of this study uses manufacturing companies listed on the Indonesia Stock Exchange for the period 2014-2016. Samples were selected using purposive sampling method with a sample size of 291. This study used multiple linear regression analysis with SPSS 16.0. The results of this study indicate that the structure of assets, company size and business risk does not have a significant effect on capital structure, profitability has a negative and significant effect on capital structure, and growth rates have a positive and significant effect