Palm oil exports in 2016 decreased by 13.95 percent. One of the reasons is because of the disturbance of leaf-eating caterpillars of Palm Oil or Caterpillar Flame (Setora nitens). It is known that the fermentation and extraction of Bacillus thuringiensis and Lantana camara can reduce the caterpillar pest population. The aim of the study was to determine the effectiveness of biopesticide B. thuringiensis and L. camara in a liquid fermentation formula plus the results of solid extraction to control palm oil caterpillar. Experimental research arrangged in Completely Randomized Design (CRD), with single factors experimental design that are biopesticide formula fermented by B. thuringiensis and L. camara on POME medium and coconut water with the addition of extraction results consisting in 5 treatments: (A) 5% extraction results, (B) 10% extraction results, (C) 15% extraction results, (D) 20% extraction results, (E) 25% extraction results. The researcher observed physical changes during fermentation (temperature, pH, color, aroma, and TDS), population dynamics and identification of B. thuringiensis, and Bioassay testing of caterpillars on palm oil. The results showed that during the fermentation process there was a change in temperature up to 28oC, pH 4.27, color Dark brown, pungent aroma, and an increase of TDS value up to 2196 ppm. The Bioassay results showed a liquid fermentation formula plus a solid extraction yield of 20% solid material extraction can control caterpillar populations. The parameters used were mortality (%), efficacy (%), and speed of death (days). L. camara extract liquid formula after fermentation with B. thuringiensis with 20% solid material extraction has 77.33%a mortality, 2.87 death rate, and 80% efficacy.