Learning media is a tool for communication between students and teachers, so that the learning process becomes more effective. Lembar Kerja Siswa (LKS) or also known as Student Worksheet as one of printed media in the learning process is commonly used by the schools in Indonesia. This research aimed to find out the benefits of the use of LKS as learning media perceived by Senior High School students and the challenges faced by Senior High School students in using LKS as learning media. This research was conducted at a private senior high school in Yogyakarta involving four students as research participant. This research employed descriptive qualitative design as the research design to present the findings found in this research. In collecting the data, in-depth interview was used in this study. The finding showed the benefits of using LKS as learning media perceived by Senior High School students. Those findings were can understand the material faster, can practice more question types, can be used anywhere and anytime, and less pricey. In addition, the finding also presented the challenges faced by Senior High School students in using LKS as learning media. Those second findings were the material in the LKS is incomplete explanation, ambiguous answers, and lack of face validity.