The purpose of this sutdy was to determine the effect of profitability, tangibility, liquidity and age to the capital structure of manufactur company. This research was conducted in the Indonesia Stock Exchange with the period 2015 – 2018. The method of determining the sample is nonprobabilistic purposive sampling with a sample of 117 companies enganged in manufacturing industry. The analysis technique used in this study is the technique of multiple liniar regression analysis. The findings indicate that profitability, tangibility, and liquidity patrially significant negative effect on the capital structure of the manufacture industries in Indonesia Stock Exchange in 2015 – 2018, while the age of the company has no significant effect on the capital structure of the manufacture industry in Indonesia Stock Exchange from 2015 – 2018.