The focus of this research relates to the Muslim Migrants of Jayapura Regency in dealing with the dynamics of Papua in the era of the enactment of Special Autonomy. The problem of research is why Muslim migrants are able to withstand various pressures in the era of Special Autonomy in Papua. This research method uses a qualitative approach to data acquisition through observation, interviews and documentation studies. The results of this study indicate that the privileges obtained by Papuans cause segmentation between Papuans and migrants leading to dominance. This privilege makes Muslim Migan have to adapt, contest and at the same time negotiate in building relations with the Indigenous Papuans (OAP) with various patterns. In the social field, the relation is in the form of contestative-accommodative; in the political field occurs in a pattern of contestative-affirmative relations and in the economic field the relationship takes place in a symbiotic-mutualistic relationship. To maintain self-existence, migrants then construct themselves in the midst of the dynamics of Papuan politics with their capital by mobilizing capital resources, especially in the informal economic sector, and those factors are also carried out by migrants when they feel in a state of "subordinated" by building their identity which is called identity politics. This dissertation confirms that the application of Papua's special autonomy needs to be evaluated in terms of equalization of citizens. Papuans on the pretext of affirmation from the state can just play a "cultural strategy" when dealing with other citizens to achieve desires both social, political and economic aspects. So for the government, constructing rules of legislation should pay attention to the values and local wisdoms and the values of community religiosity, both Indigenous Papuans (OAP) and migrant community groups, so that harmony in society can be maintained.