Video is a promising, relevant, and increasingly used form of learning media that can improve the quality of education. This study aims to further examine the use of video as a learning strategy in supporting the knowledge and clinical skills of nursing students. This study using a quasi-experimental design with a pretest and posttest to compare video methods and lecture methods in nursing students. The research sample population was 60 respondents and the research data collection method used the MCQ (Multiple Choice Question) questionnaire sheet for the assessment of the knowledge, while the OSCE (Objective Structured Clinical Examination) sheet for the assessment of students' clinical skills. Based on the results of research using paired t-test, posttest t-test, and hypothesis testing using independent sample t-test that the value of t count > t table (pvalue = 0,000 < 0.05), so that the value is significant in improving both aspects the assessment. The results showed that scores for clinical knowledge and skills in the intervention group were higher than the control group. Flexible learning videos can be done repeatedly to make it easier to remind the material, whereas conventional methods only focus on explanations and cause students to be less active in the process. The use of video can increase the effectiveness of learning can be more effective than conventional methods on nursing students