THE EFFECT OF PHOENIX DACTYLIFERA POLLEN ON HISTOLOGY LIVER OF RATTUS NORVEGICUS EXPOSED WITH AIR FRESHENERS
DEWI, MEGA SILVIANA
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Air freshener contains formaldehyde that has toxic effects on the liver. The damage can be reduced by antioxidants. Date palm pollen contains flavonoids and phytochemicals that are known to have hepatoprotective effects. This research aimed was to assess the effectiveness of date palm pollen on liver histology due to exposure of air freshener. A quasi-experimental study with a post-test only controls group design. Thirty two male rats (Rattus norvegicus) divided into eight groups, the control group (C); exposed air freshener 4 hours/day (P); given date palm pollen with a dose of 120 mg/kg BW, 240 mg/kg BW, and 360 mg/kg BW (K1, K2, K3); and exposed to air freshener 4 hours/day and given date palm pollen with a dose of 120 mg/kg BW, 240 mg/kg BW, and 360 mg/kg BW (PK1, PK2, PK3). The treatment of the subject given for 30 days. The liver histological damage assessed use Manja Roenigk's scoring. Data analysis used statistical tests One Way ANOVA and post hoc Duncan. Exposure to date palm pollen has a positive effect on reducing liver histology damage scores in K2, K3, PK1, PK2, and PK3 groups, indicated by the absence of significant differences with C group. Group K1 had a score approach P group that significantly different from the C group.