Self care agency was a complex ability of individuals to fulfill their daily needs. Children with disabilities (mentall disabled and blind) had less the self care ability and dependent with their parents. It could influence their dependent to did daily activities such as ate, drunk, elimination, and others. It was become one of special nurses concern about the self care ability on the children with disabilities. Objective : The aim of this research was to describe the self care agency on children with disabilities (mental disabled and blind) based on respondent characteristics such as class, aged, gender, medical history, and the tribe or culture. Methods : The research design was use quantitative descriptive with survey approach. Samples were 85 children with mental disabled and blind was age 6-18 years old. The sampling technique used purposive sampling technique. Data were analyzed use descriptive statistics. Research instrument were use a questionnaire developed based on the theory of Orem. Results : The results showed that self care agency on children with disabilities (mental disabled and blind) were dominated with enough category 38 children (44,7%). The Description of Self Care Agency on Children with disabilities (mental disabled and blind)based on respondent characteristic, as much as 29 children (42,6%) of mental disable class with good categorize, as much as 24 children (49%) of male with enough categorize, as much as 18 children (48,6%) was age 6-11 years old with enough categorize, as much as 19 children (51,4%) was age 12-16 years old with enough categorize, as much as 27 children (50,9%) was elementary school level with enough categorize and as mjuch as 15 children (52,22%) who respondents didn’t have history of health with enough categorize. Conclusions and Recommendations : Self care agency on children with disabilities (mental disabled and blind) was enough. Researcher suggest to the next research to did a qualitative research to explore self-care agency on the children with disabilities.