This research aims to assess the scientific creation of the universe in the content of the Qur'an by Harun Yahya on his work The Qur'an Leads the Way to Science and describes it implementation to the Islamic education. This research used descriptive qualitative with the type of research library. There are two types of data sources: primary and secondary. The primary data source was Harun Yahya's work The Qur'an Leads the Way to Science. Secondary data sources were books and the others research wich relevant to this research. From this research known that on the Harun Yahya’s work The Qur'an Leads the Way to Science discussed the importance of religion to science. The most dominant science discussed on this book was about the origins of the universe and the creation of man. Science creation of the universe could be implemented at Islamic education, by integrated it into subjects of Pendidikan Agama Islam (PAI) as a form of Islamic education in schools. In the application, the integration of PAI with science can be contained in the curriculum that consists of objectives, materials, methods and evaluation: (1) The purpose of Islamic education not only foster human to be able to implement the teachings of Islam. But also strengthen the human belief that Allah was the only one God, by studied the original creation of the universe and the creatures and events in it. (2) the material presented in the PAI included not only religious teachings but also the scientific facts that supported the teachings of the religion. (3) a method that could be applied was integrative learning model. (4) evaluation used in the evaluation as well as other subjects, there were by used variety of evaluation tools and suitable material that has been delivered. Because of the material presented was integration of PAI with science, then the evaluation form too.