The study aims to analyze the influence of Job Motivation on Employee Preformance with Job Satisfication As Intervening Variabel. Subject in this study were employees of RS PKU Muhammadiyah Gamping. Methods in this study using the census technique that all employees can be respondents in the study The analysis tool used is Structural Equation Modeling (SEM) Amos 22. Based on the analysis that has been done,it is found that Job Motivation has a significant positive effect on employee Job Satisfaction, Job Satisfaction has a significant positive effect on employee performance, Job Motivation has a significant positive effect on employee performance and Job Motivation has a siginificant positive effect on employee performance through job satisfaction as intervening.