This study analyzes the role of mediation of job satisfaction in the relation of distributive justice and ethical leadership to organizational commitment at PKU Muhammadiyah Yogyakarta, this research for companies as decision-making to keep employees committed to the organization. Organizational commitment to employees is formed because of the fairness given by the company. This can shape the desired attitudes and behavior of employees such as satisfaction with the results of decisions and commitment to work. The subjects in this study were nurses of RS. PKU Muhammadiyah Yogyakarta, the data used in this study were quantitative data with primary data. The sample in this study used a census method, the data in the form of questionnaires were distributed directly to 212 respondents, data analysis techniques used AMOS SEM. The results showed that: 1) distributive justice has a significant positive effect on job satisfaction 2) ethical leadership has a significant positive effect on job satisfaction 3) job satisfaction has a significant positive effect on organizational commitment 4) distributive justice has a positive effect on organizational commitment 5) ethical leadership has a positive effect significant to organizational commitment 6) distributive justice has a significant positive effect on organizational commitment mediated by job satisfaction 7) ethical leadership does not affect organizational commitment mediated by job satisfaction