Spirituality is an important aspect of palliative care. Provoding spiritual needs to patients can improve the quality of life of patients with chronic diseases. The purpose of this research is to know the spiritual status of palliative patients in PKU Muhammadiyah Gamping Yogyakarta Hospital. This research is a non-experiment research used descriptive survey research method. The sample in this study was taken used the technique of total sampling with time limit of 100 respondents. The instrument of this study used FACIT-Sp questionnaire which has been translated into Indonesia and has been tested Validity (r=0,50) and Reliability (r=0,768). The result of univariate analy sis showed that the spiritual level of palliative patients in PKU Muhammadiyah Gamping Hospital with the mean values of 36,79 (0-48) and the spiritual component consisted of mean, faith and peace obtained mean values of each component is 12,26; 12,85 and 11,68 (0-16). The spiritual status of palliative patients at Muhammadiyah Gamping Yogyakarta Hospital, in the categories of meaning, faith, peace and spiritual level most have passed the cut of point, it showed that the palliative patient is headed to the good spiritual. Based on this research Hospital expected to improve the service of psychospiritual nursing care in patients.