CV Pendawa Kencana Multyfarm is a company that produce three probiotics such as Profeed, which enhanced nutrient absoption through livestock’s feed, Propunic which functioned as a decomposer for making an organic fertilizer, Proquatic which enhanced pond water quality. This research aim to describe marketing mix application of various probiotics in CV Pendawa Kencana Multyfarm. This research used quantitative description method with case study as its research implementation method. Responden determination method used purposive sampling. Data type used primer and secondary data. Collecting data used observation, interview, and documentation. Data analysis method used descriptive method. The result showed that marketing mix application in CV Pendawa Kencana Multyfarm included on the very good category with 171,25 as its score, or 88,87% as its percentage.