Background: Transition period occurs among freshmen experiencing adaptation process with their college environment. During the adaptation, freshmen experience psychological problems on learning method changes since the students still implement the learning styles they had when they were in high schools. Multiple Choice Questions (MCQ) is a scoring with a high objectivity level conducted in each end of blocks. The students need to have optimal learning styles and learning readiness for getting good learning outcome. Research objective: To find out the correlation of Self Directed Learning Readiness (SDLR) and learning styles on the learning styles on students’ learning outcome on Multiple Choice Questions (MCQ) in Dentistry Study Program UMY in the first year blocks. Research method: Research conducted descriptive analytic with cross sectional research. The number of research respondents is 82 students and the research instruments used were questionnaires on Self Directed Learning Readiness Scales (SDLRS) and VARK (Visual, Auditory, Read-Write, Kinaesthetic). Research result: The test analysis results of Lambda show the value of p=0.178 (p>0.05), meaning that there is no significant correlation between learning styles and learning outcome Multiple Choice Questions (MCQ). The test results of Somers’d show that the value of p=0.237 (p>0.05) meaning that there is no significant correlation between learning styles and learning outcome of Multiple Choice Questions (MCQ). Conclusion: There is no correlation between Self Directed Learning Readiness (SDLRS) and learning styles on learning outcome of students of Dentistry Study Program in the first year blocks.